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There are numerous protests about Trump. I was impressed by Michael Moore's call to action on his Facebook page --  creative dissent at its best and a template for the organizing of any other  kind of public protest. (From the Huffington Post)

Do These 10 Things, and Trump Will Be Toast

10-POINT ACTION PLAN TO STOP TRUMP

1. THE DAILY CALL: You must call Congress every day. Yes - YOU! 202-225-3121. It will take just TWO MINUTES! Make it part of your daily routine, one of those five things you do every morning without even thinking about it:

1. Wake up.

2. Brush teeth.

3. Walk dog (or stare at cat).

4. Make coffee.

5. Call Congress.

It is impossible to overstate just how much power you have by making this simple, quick DAILY CALL. I know from firsthand experience the impact it has. These politicians freak out if they get just 10 calls on an issue. Imagine them getting 10,000! Holy crap - the dome will pop off that building!

NOTE: if you're saying to yourself, "I don't need to call because my rep is a Democrat!" -- that is NOT true. They need to hear from you. They need to know they have your support. Don't believe it? Our beloved Sen. Elizabeth Warren voted in favor of Ben Carson as Secretary of Housing and Urban Development! I'm sure no one in Massachusetts thought they had to call her. YOU DO! She and the other Dems need to hear from the boss -- YOU! They work for us - and what boss doesn't have daily contact with his or her employees?

It's easy to make The Daily Call. To call your U.S. member of Congress or Senators in D.C., dial 202-225-3121 (or 202-224-3121 if busy). It's even better to call their direct line. For Senators, find each of their numbers here: http://bit.ly/2kko0Ao. For the direct line to your member in the House of Representatives: http://house.gov/representatives

Here’s some great news: Someone has created an app to make this very easy: Go to the App Store and get "5 Calls". The app will dial the friggin' phone for you and give you talking points for when you speak to your reps!

Here's what a sample week of your DAILY CALL can look like:

On Monday, call your Congressman/woman and tell them you do not want them to repeal Obamacare. In fact, you want them to improve it so that we have single-payer universal health care like all other "civilized" countries.

On Tuesday, call the first of your two U.S. Senators and tell him to vote NO on Rick Perry for Secretary of Energy. He couldn't even remember there was a Department of Energy - or what it did!

On Wednesday, call your other U.S. Senator. Demand she do everything in her power to block the appointment of Neil Gorsuch to the U.S. Supreme Court.

On Thursday, call your local State House/Assembly representative in your state capital. Tell her you want the House to vote for legislation that prohibits the incarceration of nonviolent drug users.

On Friday, call your State Senator. Tell him you want him to support all efforts to reduce those activities which cause climate change.

If you’d rather to write to your reps, you can find the best way to do that for each of them here by typing in your address on: democracy.io.

I will post updates on the actions we're fighting for each day and week on my Twitter and Facebook pages. If you want to know what to call your reps about, I encourage you to follow me right now on Facebook at facebook.com/MMFlint and on Twitter at @MMFlint. All my social media sites are at my website www.michaelmoore.com.

Remember -- A call a day keeps the Trump away.

2. THE MONTHLY VISIT: To add even more pressure, SHOW UP! Your member of Congress has a local office in your town or somewhere nearby. So do both of your U.S. Senators (often in the nearest federal building). Go there and ask to speak to their aide about the issues we're facing (again, I will continually post them on my social media sites).

Also, don't forget to visit the local office (or the state capitol office) of your State Representative/Assemblyperson, and your State Senator.

And, if you're lucky to live within driving distance of Washington, DC, show up on Capitol Hill and pay an unannounced (it's legal!) in-person visit to your U.S. Senators and your Congressman/woman. They pay serious attention to this. It blows their mind that you'd drive that far to see them. Do it!

I know not everyone has the time to do THE MONTHLY VISIT -- but if you can, please do!

3. YOUR OWN PERSONAL RAPID RESPONSE TEAM: You and 5 to 20 friends and family members must become your personal RAPID RESPONSE TEAM. Sign everybody up so that when we need to leap into action (like we did at the airports the hour after Trump signed his Muslim Ban), you can email and text each other and make an instant plan. On other days, you'll share links to good investigative stories and TV news items. Come up with a name for your RAPID RESPONSE TEAM -- mine is called "The V for Vendetta Rapid Response Team" and it consists of myself, my daughter and son-in-law (and their new baby!); my two sisters, their spouses and adult children; my cousin; 8 friends; 6 co-workers; and my next door neighbor. That's 27 of us and we live from Seattle to Michigan to Maryland. And each of them are forming their own local Rapid Response Teams. So that means the 27 on my team are so far responsible 405 new Rapid Responders overnight! And each of those 405 are doing the same - they're recruiting their own 5-20 people - and BOOM! 4,050 more Rapid Responders tomorrow -- and growing!

4. JOIN! JOIN! JOIN!: We all know it's time for all of us to be part of a greater whole, so let's actually physically sign up online and JOIN some of our great national groups. I've joined Planned Parenthood, ACLU, Black Lives Matter, Democratic Socialists of America, and ERA Action. Some charge money to join, so if you don't have much, pick the lowest amount ($5 for ACLU for example) -- or join groups that don't charge anything (but if you can help them financially, please do). They will keep you informed of national actions and fight for us in court.

5. THE WOMEN'S MARCH NEVER ENDS: The historical, record-breaking January 21st Women’s March on Washington -- and the hundreds of other Marches that day across the US and the world, with over 4 million in attendance! -- brought massive numbers of people out who had never protested in their lives. It inspired millions of others and ignited so many local movements we still can't count them all. The day after the Women's March, another two dozen protests took place. The day after that, 2,000 Utahans jammed into their state capitol in Salt Lake City. Then, on the following Saturday, tens of thousands of Americans occupied their local airports to oppose Trump's Muslim ban. And on and on and on. Every day -- still! -- dozens of actions continue to take place as if the Women's March never ended. It hasn't. Join it!

I and a group of friends have set up THE RESISTANCE CALENDAR (www.resistancecalendar.com) that is updated daily, where you can find out what actions are taking place near where you live. All you have to do is type in your city or state in the search bar.

It's critical that large numbers of us continue to march, protest, sit-in, and be very visible -- to Trump, so he knows we are the majority; to put the Dems on notice that we expect them to grow a spine; to our fellow Americans who live in Boise or Tulsa or Grand Rapids and have been feeling alone and afraid since the election. Our mass presence reminds them the people didn't elect Trump. And it is good for each of us to operate in concert with each other, to feel the solidarity and the hope.

And the official Women's March on Washington -- they've called for a national Women's Strike on March 8th. Let's join them!

6. TAKE OVER THE DEMOCRATIC PARTY: The old guard of the Party has twice in 16 years presided over the majority of Americans electing the Democrat to the White House -- only for us all to see the losing Republican inaugurated as President. How is it that we have won the popular vote in SIX OF THE LAST SEVEN PRESIDENTIAL ELECTIONS -- the Republicans have only won ONCE since 1988 -- and yet, we hold NO power in any branch of government?! That, plus losing 1,000 local seats in this election that the Dems use to hold -- plus watching many Dems in Congress unwilling to stand up to Trump -- PLEASE, the old leadership has to go. God love 'em for their contributions in the past, but if we don't enact a radical overhaul right now, we are doomed as far as having a true opposition party during the Trump era. And that, more than anything, will help to usher in the vice-grip of a totalitarian culture.

You must do two things:

1. Let the DNC know that THIS SATURDAY, February 25th, the Democratic National Committee MUST elect reform and progressive candidate, Congressman Keith Ellison, as the new DNC chair. Keith is a former community organizer, the first Muslim elected to Congress, and a key backer of Bernie Sanders. He not only has Bernie's support --and mine--but he's also backed by Chuck Schumer, Harry Reid, Gloria Steinem, John Lewis and many others. Sign his petition of support at www.keithfordnc.org/howyoucanhelp. Let the DNC know how you feel.

And locally, you need to start attending your county Democratic meetings. If possible, organize your friends and others and take over your local Dem organization. More on this at a later date.

7. HELP FORM BLUE REGIONS OF RESISTANCE: People keep saying to me, "Mike - I live in a Blue State - what can I do?" If you live in a Blue State, you have one of the MOST important tasks to complete: Show the rest of America what it looks like when Trump isn't in charge! Blue States and Blue Cities must do an end-run around Trump and create the America we want to live in. That means New York goes ahead and offers Free College for All. California can create its own Universal Health Care. Oregon can stop mass incarceration of African Americans. Hawaii can enact its own climate change laws. Blue States can show the rest of country how much better life can be. Important historical note: Before Roe v. Wade made abortion legal, California and New York passed their own state laws to make it legal. This greatly helped pave the way for CHOICE being the new normal -- and the enactment of Row v. Wade.

8. YOU MUST RUN FOR OFFICE: I know, that's the LAST thing you want to do. But if we keep leaving the job up to the dismal, lame, pathetic political hacks who have sold us all down the river, then what right do we have to complain? This is only going to get fixed when you and I decide we are willing to put in our time -- even if it is a brief time -- and run for office. I ran when I was 18 and got elected. You can, too. We need good candidates for the 2018 elections -- and not just Congress and State Houses, but also school boards, city councils and county commissions. Why not take out a petition today and run next year? Heck, I'll bet I'll even support you!

I realize most of you can't do this -- but there is one office every one of us can and SHOULD run for next year: PRECINCT DELEGATE. Every precinct, every neighborhood can elect x-number of Dems to the county Democratic Convention. It's on the ballot and it's usually blank - no one runs for it. So the precinct delegates end up being appointed by the party hacks. And that's who ends up eventually at the national convention to pick the next presidential candidate. So this is an important position to run for. The time commitment is just 3 hours a year! You attend the county convention -- that’s it. Call your city or county clerk and find out how to get on the ballot. If you'll do it, I'll do it. It's the first step to making sure we put a candidate on the ballot who can win.

9. YOU MUST BECOME THE MEDIA: Stop complaining about the media, stop wishing they were something they're not, find the ones who are doing a good job and then start your own "media empire" by sharing their work and your work on the internet. Use Facebook, Twitter, Instagram, Snapchat and other social media sites to spread news and information. Make sure all your friends and family are signed up. Yes, I'm talking to you, Baby Boomers. Get over it, put down your postage stamps and your "TV clicker" and find a six-year old to show you how to start tweeting. You can be your own reporter, your own editor. You can curate the news for your friends. And now Facebook lets you have your own network with Facebook Live! It's all free. Get on social media now. Imagine, your own CNN is in the palm of your hand...

10. JOIN THE ARMY OF COMEDY: Trump's Achilles heel is his massively thin skin. He can't take mockery. So we all need to MOCK HIM UP! Not just the brilliant people at SNL or Colbert, Seth Myers or Samantha Bee -- but YOU. Use your sense of humor and share it with people. Get them to do the same. Keep sending around the SNL links spoofing Sean Spicer, Trump and Kellyanne -- there's no such thing as watching them too many times! Hahaha. I truly believe the final tipping point for Trump will be when he implodes from all the laughter -- the mocking, the unbearable ridicule of tens of millions of Americans that will discombobulate him and force him out of the White House. I know this seems like Mike’s fever dream, but I believe it can work. I don't know what happened to Trump in boarding school at 13 and I don't care. Whatever it was, let's use it. He's used all the other things he picked up over the years - misogyny, bigotry, greed - against the powerless and the unfortunate. It's time to laugh him outta town. And if there's one thing we all could use right now is a good laugh -- AND the possibility of a much-shortened presidential term.

So, there you go! The 10-Point Action Plan to Thump Trump. Something for everyone. And every one of us needs to do them. Please share this and spread the word. We can stop him. We can nonviolently block and obstruct halt the damage he's doing. But it's going to need -- and take -- ALL HANDS ON DECK!

Let's make Trump toast again.

-- Michael Moore

Jennifer Doudna - co-inventor of the CRISPR technology talks about the need for 'ethics of CRISPR'.

Following on the issues raised in a previous post, Jennifer and numerous colleagues have called for an international meeting to discuss the safe use of CRISPR and the ethics of being able to create "engineer humans" as well as other genetically modified organisms (GMO's)

It is important that all stake holders (excuse the jargon), which includes you and me, understand the potential and risks of this technology and to have an informed discussion in accordance with the principles of a pluralist democracy. For more , click here.

For an elegant explanation of the CRISPR-Cas9 system watch the video.

A groundbreaking experiment on quantum entanglement puts the final nail in the coffin of our ordinary view of the universe, settling an argument that has raged for nearly a century.

(from the NewScientist | 5 September 2015 pp 8-9)

To understand the experiment, we have to go back to the 1930s, when physicists were struggling to come to terms with the strange predictions of the nascent science of quantum mechanics. The theory suggested that particles could become entangled, so that measuring one would instantly the measurement of the other, even if they were far apart.

Einstein famously proclaimed that God does not play dice with the universe and called entanglement "spooky action at a distance". He and others favoured the principle of local realism, which broadly says that only nearby objects can influence each other and that the universe is "real" - observing it doesn't bring it into existence by crystallising vague probabilities.

They argued that hidden variables at some deeper layer of reality could explain quantum theory's apparent weirdness. On the other side, physicists like Niels Bohr insisted that we accept the new quantum reality, because it explained problems that classical theories of light and energy couldn't handle.

Quantum-weirdness

In this set-up, Alice and Bob sit in two laboratories 1.3 kilometres apart, far enough to close the locality loophole. Each laboratory has a diamond containing an electron with a property called spin. The team hits the diamonds with randomly produced microwave pulses. This makes them each emit a photon that is entangled with the electron's spin. These photons are sent to a third location, C, where a device clocks their arrival time. If photons arrive from Alice and Bob at exactly the same time, the two electron spins become entangled with each other. The result was clear: they detected more highly correlated spins than local realism would allow. (For the Abstract, click here). The weird world of quantum mechanics is our world.

This raises the bar for other possibilities; Is the brain a quantum computer?

Professor Stuart Hameroff

On the face of it the weirdness of quantum mechanics and biology would seem to have nothing to do with each other. Quantum mechanics deals with the subatomic world and biology with much larger things like cells. Any quantum effects in cells would be cancelled out by the multitude of noisy biological processes. But not so. Quantum biology refers to the many biological processes that involve the conversion of energy to usable chemical transformations and are quantum mechanical in nature.

Examples are photosynthesis, vision, magnetoreception in animals, DNA mutation, and the conversion of chemical energy into motion. Any process that involves the transfer of electrons and protons in chemical processes uses quantum mechanical effects. In photosynthesis it has been shown that the wave and particle conundrum occur simultaneously. The wave spreads uniformly to potential receptors, while the particle follows the path of least resistance through the field of potential created by the wave. This makes for a 95% efficiency in energy transfer.

Many important biological processes taking place in cells are driven and controlled by events that involve electronic degrees of freedom and, therefore, require a quantum mechanical description. An important example are enzymatically catalyzed, cellular biochemical reactions. Here, bond breaking and bond formation events are intimately tied to changes in the electronic degrees of freedom. For more quantum biology examples, click here.

Finally in neuroscience there is a debate as to whether the brain is a quantum computer -- that the microtubules within neurons have the capability to perform quantum computation . Stuart Hameroff  believes that the tubulin subunits which make up a microtubule are able to cooperatively interact in a quantum computational sense.

ebola

Recent accounts of Ebola in West Africa are terrify particularly since some cases have now spread to the US and other Western countries. At the end of the 3rd year university course in molecular virology I used to teach, the students were asked which viruses could be weaponised for bioterrorism. The usual three viruses that come up were influenza, small-pox and Ebola. All these viruses required a high degree of technological expertise and state-of-the-art laboratory containment facilities with personnel trained in molecular genetics and DNA technology. Influenza had the advantages of being an air-borne infection — the question was how easily could you reconstruct the Spanish flu of 1914 from published sequences of the virus into a current influenza virus. For small-pox, there are presumably deep freezers in the US and Russia that still have samples of the virus or one could use a close relative like camel-pox and reverse engineered it to contain the known published sequence of virulence genes of small-pox. Both of these viruses could be produced but were probably beyond the capability of your common variety terrorist.

Similarly Ebola would be difficult to produce in a laboratory due to its highly contagious nature. Ebola was initially thought to have a short incubation period of 2-3 days so the possibility of someone from a West African village boarding an airplane on an international flight seemed remote. With the incubation period now being as long as 21-days this changes everything. With the outbreak in West Africa the question of virus supply is no longer an issue — all you need is a bucket of vomit or vials of infected blood.  Also recent events have shown that a few cases of Ebola can be contained and quarantined but the health systems can not cope with hundreds or thousands of cases.

To put Ebola into perspective, it was thought to be a rarely occurring exotic virus disease in distant jungles in West Africa. Not something we in the West need concern ourselves with  — compare this to the response to SARS when it spread in Western countries. Now some 38 years later we are scrambling to understand more about Ebola. We live in a global world and need a massive global effort to get on top of this problem.

I don’t think anyone in my virology class was a potential jihadist terrorist but the world has just become more complicated.

Edward Snowden, appearing by a telepresence robot at TED2014 speaks about surveillance and Internet freedom. In the summer of 2013 The Guardian published a series of leaked documents about the American National Security Agency (NSA), starting with an article about a secret court order demanding American phone records from Verizon, followed by an article on the NSA's top-secret Prism program, said to be accessing user data from Google, Apple and Facebook. His leaks continue to have a lasting impact on the American public's view of the government, and but has also raised the hopes for both open government and individual privacy — a Magna Carta for the Internet.

Hear his views and download it so that you can show it to your grandchildren one day.

If you care about how you use Facebook — either to connect with friends, or gather information — this video is well worth watching. It clearly lets you know that Facebook is controlling your social media experience, when it should be you. Facebook is using filtering algorithms that create online ‘echo chambers’ that parrots your own views and beliefs and restricts the posts from other friends.

See more from Derek Muller, the curator of science video blog Veritasium

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In mythology, opening Pandora's Box released evil into the world instead, the Pandoravirus opens up a host of questions about the origins of life on Earth. Its discoverer, Jean-Michel Claverie at Aix-Marseille University in France , says: "We believe that those new Pandoraviruses have emerged from an ancestral cellular type that no longer exists."

Pandora
Each virus is around 1 micrometre long and 0.5 micrometres across, and their respective genomes top out at 1.9 million and 2.5 million bases — making the viruses larger than many bacteria and even some eukaryotic cells. These viruses are more than mere record-breakers — they also hint at unknown parts of the tree of life. Just 7% of their genes match those in existing databases.

How did this odd cellular form turn into a virus? Chantal Abergel says it may have evolved as a survival strategy as modern cells took over. "On Earth it was winners and it was losers, and the losers could have escaped death by going through parasitism and then infect the winner," she says.

The method used to isolate theses viruses reminds me of an undergraduate virology experiment I used to carry out with students to isolate viruses from the environment.  Claverie and his team  scooped out sediment samples from the coast of Chile and a freshwater pond in Australia. They brought back the samples and placed them in a solution filled with antibiotics, to kill any bacteria that might have been along for the ride. Then they exposed the samples to their laboratory amoebas. "If they die, we suspect that there's something in there that killed them." he said. It worked - the infected amoebas spawned lots of Pandoraviruses.

The article appeared in the journal Science.

We have become accustomed to thinking of our gut as being 'inside' us, but in fact it represents a vast area of the outside -- like a tube within a tube (our body). The gut must be able to absorb nutrients (the food we eat) but at the same time ward off invaders and harmful things we might swallow. How this occurs is becoming more and more complex as you will gather from my posts on gut bacteria -- yes, the gut must be able to accommodate the 'good' bacteria as well.

For a glimpse into this amazing world of interactions watch the video -- don't worry about the immunological details --- watch the graphics to get a sense of the wonder of it all.

(if you are using an iPad or iPhone, click here)

From NATURE: "The gut mucosa is the largest and most dynamic immunological environment of the body. It's often the first point of pathogen exposure and many microbes use it as a beachhead into the rest of the body. The gut immune system therefore needs to be ready to respond to pathogens but at the same time it is constantly exposed to innocuous environmental antigens, food particles and commensal microflora which need to be tolerated. Misdirected immune responses to harmless antigens are the underlying cause of food allergies and debilitating conditions such as inflammatory bowel disease. This animation introduces the key cells and molecular players involved in gut immunohomeostasis and disease."